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1. (WO2014198594) NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/198594    International Application No.:    PCT/EP2014/061530
Publication Date: 18.12.2014 International Filing Date: 04.06.2014
IPC:
C07D 471/04 (2006.01), C07D 487/04 (2006.01), A61K 31/4184 (2006.01), A61P 35/00 (2006.01)
Applicants: BAYER PHARMA AKTIENGESELLSCHAFT [DE/DE]; Müllerstr. 178 13353 Berlin (DE)
Inventors: SCHULZE, Volker; (DE).
SCHIROK, Hartmut; (DE).
KOSEMUND, Dirk; (DE).
BRIEM, Hans; (DE).
BADER, Benjamin; (DE).
BÖMER, Ulf; (DE).
WENGNER, Antje Margret; (DE).
SIEMEISTER, Gerhard; (DE).
LIENAU, Philip; (DE).
STÖCKIGT, Detlef; (DE).
LÜCKING, Ulrich; (DE).
SCHALL, Andreas; (DE)
Agent: BIP PATENTS; c/o Bayer Intellectual Property GmbH Alfred-Nobel-Str. 10 40789 Monheim am Rhein (DE)
Priority Data:
13171171.5 10.06.2013 EP
13198899.0 20.12.2013 EP
Title (EN) NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER
(FR) NOUVEAUX COMPOSÉS DESTINÉS AU TRAITEMENT DU CANCER
Abstract: front page image
(EN)The present invention relates to novel compounds showing an inhibitory effect on Mps-1 kinase, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.
(FR)L'invention concerne de nouveaux composés présentant un effet inhibiteur de la kinase Mps-1, des procédés de préparation de ces composés, des compositions pharmaceutiques et des combinaisons les contenant, l'utilisation de ces composés dans la fabrication d'une composition pharmaceutique destinée à la prévention ou au traitement d'une maladie, ainsi que des composés intermédiaires utiles dans la préparation de ces composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)