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1. (WO2014197725) PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/197725 International Application No.: PCT/US2014/041152
Publication Date: 11.12.2014 International Filing Date: 05.06.2014
IPC:
A61K 31/785 (2006.01) ,A61P 3/12 (2006.01)
Applicants: TRICIDA, INC.[US/US]; 1430 O'Brien Drive, Suite F Menlo Park, CA 94025, US
Inventors: KLAERNER, Gerrit; US
CONNOR, Eric, F.; US
GBUR, Randi, K.; US
KADE, Matthew, J.; US
KIERSTEAD, Paul, H.; US
BUYSSE, Jerry, M.; US
COPE, Michael, J.; US
BIYANI, Kalpesh, N.; US
NGUYEN, Son, H.; US
TABAKMAN, Scott, M.; US
Agent: HEJLEK, Edward, J.; US
Priority Data:
61/831,44505.06.2013US
Title (EN) PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION
(FR) POLYMÈRES LIANT LES PROTONS POUR ADMINISTRATION ORALE
Abstract:
(EN) Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
(FR) L'invention concerne des compositions pharmaceutiques pour le traitement d'un animal, y compris un humain, et des procédés de traitement associés, et des procédés de préparation de ces compositions. Les compositions pharmaceutiques contiennent des polymères aminés réticulés et peuvent être utilisées, par exemple, pour traiter des maladies et d'autres affections métaboliques pour lesquelles le retrait des protons et/ou des ions chlorure du tractus gastro-intestinal est susceptible d'apporter des bénéfices physiologiques, comme la normalisation des concentrations sériques de bicarbonate et du pH sanguin chez un animal, y compris un humain.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)