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1. (WO2014197607) DETECTION OF TICK-BORNE DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/197607 International Application No.: PCT/US2014/040922
Publication Date: 11.12.2014 International Filing Date: 04.06.2014
IPC:
G01N 33/569 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA[US/US]; 1111 Franklin Street, 12th Floor Oakland, California 94607-5200, US
THE JOHNS HOPKINS UNIVERSITY[US/US]; 3400 N. Charles Street Baltimore, MD 21218, US
Inventors: CHIU, Charles; US
SWEI, Andrea; US
LEE, Deanna; US
NACCACHE, Samia; US
AUCOTT, John, N.; US
SOLOSKI, Mark, J.; US
Agent: BORDEN, Paula A.; Bozicevic, Field & Francis LLP 1900 University Avenue, Suite 200 East Palo Alto, California 94303, US
Priority Data:
61/831,55605.06.2013US
61/831,56405.06.2013US
Title (EN) DETECTION OF TICK-BORNE DISEASES
(FR) DÉTECTION DE MALADIES TRANSMISES PAR LES TIQUES
Abstract:
(EN) This disclosure provides for methods to determine genetic identities of tick-borne diseases, the method comprising: immobilizing one or more polynucleotide molecules at a plurality of positions on a substrate, wherein the one or more polynucleotide molecules relate to genomic information from one or more tick-bome disease-inducing microorganisms selected from the group consisting of bacteria, protozoans, fungi and viruses; contacting a biological sample with the one or more polynucleotide molecules; obtaining hybridization information from the substrate subsequent to contacting the biological sample with the one or more polynucleotide molecules; and relating the hybridization information to information that is related to the tick-borne disease, thereby detecting the tick-born disease at a sensitivity of at least 90% or at a specificity of at least 90%.
(FR) L'invention concerne des méthodes permettant de déterminer les identités génétiques de maladies transmises par les tiques, consistant à immobiliser une ou plusieurs molécules de polynucléotides au niveau de plusieurs positions sur un substrat, la molécule ou les molécules de polynucléotides donnant des informations génomiques provenant d'un ou plusieurs micro-organismes induisant les maladies transmises par les tiques sélectionnés dans le groupe comprenant des bactéries, des protozoaires, des champignons et des virus; à mettre un échantillon biologique en contact avec la ou les molécules de polynucléotides; obtenir des informations d'hybridation provenant du substrat suite à la mise en contact de l'échantillon biologique avec la ou les molécules biologiques; et à mettre les informations d'hybridation en rapport avec des informations liées à la maladie transmise par les tiques, ce qui permet de détecter la maladie transmise par les tiques selon une sensibilité au moins égale à 90 % ou selon une spécificité au moins égale à 90 %.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)