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1. (WO2014197569) CYTOTOXIC AGENTS FOR THE TREATMENT OF CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/197569 International Application No.: PCT/US2014/040872
Publication Date: 11.12.2014 International Filing Date: 04.06.2014
IPC:
A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
CYTRX CORPORATION [US/US]; 11726 San Vicente Boulevard Los Angeles, CA 90049, US
Inventors:
LEVITT, Daniel; US
Agent:
MANGASARIAN, Karen; US
Priority Data:
61/831,21905.06.2013US
Title (EN) CYTOTOXIC AGENTS FOR THE TREATMENT OF CANCER
(FR) AGENTS CYTOTOXIQUES DESTINÉS AU TRAITEMENT DU CANCER
Abstract:
(EN) The present invention relates to a method of treating brain cancer comprising administering a therapeutically effective substance to a patient, wherein the therapeutically effective substance comprises: (I), or a pharmaceutically acceptable salt thereof, wherein X is a. moiety that can be cleaved hydrolvtically or enzymaticaily in the body of the patient in a pH-dependent manner.
(FR) La présente invention concerne une méthode de traitement d'un cancer du cerveau, comprenant l'administration d'une substance thérapeutiquement efficace à un patient. Ladite substance thérapeutiquement efficace comprend (I) ou son sel pharmaceutiquement acceptable, X étant une fraction qui peut être clivée hydroliquement ou enzymatiquement dans le corps du patient d'une manière dépendante du pH.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)