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1. (WO2014197477) TRANS-CLOMIPHENE AND ITS ANALOGUES AS AGENTS THAT INCREASE BONE MINERAL DENSITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/197477    International Application No.:    PCT/US2014/040704
Publication Date: 11.12.2014 International Filing Date: 03.06.2014
IPC:
A61P 19/10 (2006.01)
Applicants: REPROS THERAPEUTICS INC. [US/US]; 2408 Timberloch Place, Suite B-7 The Woodlands, TX 77380 (US)
Inventors: PODOLSKI, Joseph, S.; (US).
HSU, Kuang; (US).
WIEHLE, Ronald, D.; (US).
FONTENOT, Greg; (US).
THOMPSON, Jaye; (US)
Agent: CLOUGH, David, W.; (US)
Priority Data:
61/831,542 05.06.2013 US
Title (EN) TRANS-CLOMIPHENE AND ITS ANALOGUES AS AGENTS THAT INCREASE BONE MINERAL DENSITY
(FR) TRANS-CLOMIPHÈNE ET SES ANALOGUES COMME AGENTS QUI AUGMENTENT LA DENSITÉ MINÉRALE OSSEUSE
Abstract: front page image
(EN)The present invention relates to the administration of compositions comprising trans-clomiphene or an analogue or salt thereof, for inhibiting bone resorption and bone turnover in a subject. The invention is also directed to methods for increasing bone mineral density in a subject and preventing or treating a bone related disorder in a subject comprising administering to the subject an effective amount of trans-clomiphene or an analogue or salt thereof.
(FR)La présente invention concerne l'administration de compositions comprenant du trans-clomiphène ou son analogue ou son sel pour inhiber la résorption osseuse et le remodelage osseux chez un sujet. L'invention concerne également des procédés permettant d'augmenter la densité minérale osseuse chez un sujet et de prévenir ou traiter un trouble lié aux os chez un sujet consistant à administrer au sujet une quantité efficace de trans-clomiphène ou de son analogue ou de son sel.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)