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1. (WO2014195888) DUAL SELECTIVE PI3 DELTA AND GAMMA KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2014/195888 International Application No.: PCT/IB2014/061954
Publication Date: 11.12.2014 International Filing Date: 04.06.2014
IPC:
C07D 473/04 (2006.01) ,A61K 31/52 (2006.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
473
Heterocyclic compounds containing purine ring systems
02
with oxygen, sulfur, or nitrogen atoms directly attached in positions 2 and 6
04
two oxygen atoms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
52
Purines, e.g. adenine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
RHIZEN PHARMACEUTICALS SA [CH/CH]; Fritz Courvoisier 40 CH-2300 La Chaux-de-Fonds, CH
Inventors:
VAKKALANKA, Swaroop K. V. S.; CH
BHAVAR, Prashant K.; IN
VISWANADHA, Srikant; IN
BABU, Govindarajulu; IN
Priority Data:
2501/CHE/201307.06.2013IN
5567/CHE/201303.12.2013IN
Title (EN) DUAL SELECTIVE PI3 DELTA AND GAMMA KINASE INHIBITORS
(FR) INHIBITEURS BI-SÉLECTIFS DELTA ET GAMMA DES KINASES PI3
Abstract:
(EN) The present invention relates to dual delta (δ) and gamma (γ) PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of Pi3K kinase mediated diseases or disorders with them.
(FR) La présente invention concerne des doubles modulateurs delta (δ) et gamma (γ) des protéines kinases PI3K, des procédés pour leur préparation, des compositions pharmaceutiques les contenant et des méthodes qui permettent de traiter, de prévenir et/ou d'atténuer les effets de maladies ou de troubles dont la médiation est assurée par une kinase Pi3K au moyen de ceux-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA2913226SG11201509992RKR1020160017047CN105358560EP3004106EA201592113
NZ714465AU2014276476ID2017/07591MYPI 2015002884PH1/2015/502698BR112015030385
TH169359ES2648094IN7976/CHENP/2015IL242761