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Machine translation
1. (WO2014195521) POLYPEPTIDES WITH PERMEASE ACTIVITY
Latest bibliographic data on file with the International Bureau   

Considered void 18.03.2015


Pub. No.: WO/2014/195521 International Application No.: PCT/EP2014/063069
Publication Date: 11.12.2014 International Filing Date: 20.06.2014
IPC:
C07K 14/395 (2006.01)
Applicants: DSM IP ASSETS B.V.[NL/NL]; Het Overloon 1 NL-6411 TE Heerlen, NL
RIJKSUNIVERSITEIT GRONINGEN[NL/NL]; Broerstraat 5 NL-9712 CP Groningen, NL
Inventors: KLAASSEN, Paul; NL
DE WAAL, Paulus Petrus; NL
DE JONG, René Marcel; NL
DRIESSEN, Arnold Jacob Mattieu; NL
NIJLAND, Jeroen Gerben; NL
SHIN, Hyun Yong; NL
Agent: KLEIBORN, Paul Erik; NL
Priority Data:
13197988.218.12.2013EP
14160772.119.03.2014EP
14164270.210.04.2014EP
Title (EN) POLYPEPTIDES WITH PERMEASE ACTIVITY
(FR) POLYPEPTIDES AYANT UNE ACTIVITÉ PERMÉASE
Abstract:
(EN) The invention relates to a polypeptide having one or more substitution at a position corresponding to position 339 or 376 of SEQ ID NO: 59, wherein the polypeptide is a member of the Major Facilitator Superfamily (MFS). In an embodiment, the substitution is at position corresponding to 376 and wherein the amino acid at that position is replaced by an amino acid that has a van der Waals volume of 80 to 138 Å3 and a side chain hydrophobicity of 10 to 100 ΔtR.
(FR) Cette invention concerne un polypeptide comportant une ou plusieurs substitutions à une position correspondant à la position 339 ou 376 de SEQ ID No: 59, le polypeptide étant un membre de la superfamille majeure de Facilitateurs (MFS). Dans un mode de réalisation, la substitution est à la position correspondant à 376 et l'acide aminé à cette position est remplacé par un acide aminé ayant un volume de van der Waals de 80 à 138 Å3 et une hydrophobicité de chaîne latérale de 10 à 100 ΔtR.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)