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1. WO2014194956 - DERIVATIVES OF [1, 2, 4] TRIAZOLO [4, 3 - A] PYRIDINE AS P38 - MAP KINASE INHIBITORS

Publication Number WO/2014/194956
Publication Date 11.12.2014
International Application No. PCT/EP2013/061706
International Filing Date 06.06.2013
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
437
the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
C07D 471/04 (2006.01)
A61K 31/437 (2006.01)
A61P 11/06 (2006.01)
CPC
A61K 31/437
C07D 471/04
C07D 519/00
Applicants
  • CHIESI FARMACEUTICI S.P.A. [IT/IT]; Via Palermo, 26/A I-43100 Parma, IT
Inventors
  • ALCARAZ, Lilian; IT
  • PANCHAL, Terry Aaron; IT
  • JENNINGS, Andrew Stephen Robert; IT
  • CRIDLAND, Andrew Peter; IT
  • HURLEY, Christopher; IT
Agents
  • MINOJA, Fabrizio; Bianchetti Bracco Minoja S.R.L. Via Plinio, 63 I-20129 Milano, IT
Priority Data
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DERIVATIVES OF [1, 2, 4] TRIAZOLO [4, 3 - A] PYRIDINE AS P38 - MAP KINASE INHIBITORS
(FR) DÉRIVÉS DE [1, 2, 4] TRIAZOLO [4, 3 - A] PYRIDINE UTILES EN TANT QU'INHIBITEURS DE P38 - MAP KINASE
Abstract
(EN)
This invention relates to compounds selected in the group consisting of compounds of formula (la) to (Id) and compositions, that are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
(FR)
La présente invention concerne des composés sélectionnés dans le groupe constitué de composés de formule (la) à (Id) et de compositions, qui sont des inhibiteurs de p38 MAPK, utiles en tant qu'agents anti-inflammatoires dans le traitement, entre autres, des maladies des voies respiratoires.
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