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1. (WO2014194551) BIOSYNTHESIS GENE CLUSTER OF MARINACARBOLINES AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/194551    International Application No.:    PCT/CN2013/079434
Publication Date: 11.12.2014 International Filing Date: 16.07.2013
IPC:
C12N 15/11 (2006.01), C12N 15/52 (2006.01), C12N 9/00 (2006.01), C12P 17/18 (2006.01)
Applicants: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY,CHINESE ACADEMY OF SCIENCES [CN/CN]; No.164, West Xingang Road, Haizhu Guangzhou, Guangdong 510301 (CN)
Inventors: JU, Jianhua; (CN).
CHEN, Qi; (CN).
JI, Changtao; (CN)
Agent: GUANGZHOU KEYUE I.P.LAW OFFICE; Room 616,6/F,Building 23-1,No.100,Xianlie Central Road, Yuexiu Guangzhou, Guangdong 510070 (CN)
Priority Data:
201310224447.2 06.06.2013 CN
Title (EN) BIOSYNTHESIS GENE CLUSTER OF MARINACARBOLINES AND USE THEREOF
(FR) FAMILLE DE GÈNES BIOSYNTHÉTIQUES CODANT POUR LES MARINACARBOLINES ET SON UTILISATION
(ZH) 一种海洋咔啉生物碱的生物合成基因簇及其应用
Abstract: front page image
(EN)Disclosed are a biosynthesis gene cluster of marinacarbolines (MCBs) and a use thereof. The nucleotide sequence of the gene cluster is as shown by positions 1-4222 of SEQ ID NO. 1, and comprises three genes: a gene mcbA responsible for the synthesis of the amide linkage of the MCBs, a gene mcbB responsible for the Pictet-Spengler reaction of MCBs, and a gene mcbC responsible for the decarboxylation of the MCBs.
(FR)L'invention porte sur une famille de gènes biosynthétiques codant pour les marinacarbolines (MCB) et l'une de ses utilisations. La séquence nucléotidique de la famille de gènes est telle que représentée par les positions 1 à 4222 de la SEQ ID nº 1, et elle comprend trois gènes : un gène mcbA responsable de la synthèse de la liaison amide des MCB, un gène mcbB responsable de la réaction de Pictet-Spengler des MCB et un gène mcbC responsable de la décarboxylation des MCB.
(ZH)一种海洋咔啉生物碱(marinacarbolines,MCBs)的生物合成基因簇及其应用。该基因簇的核苷酸序列如SEQ ID NO.1的第1-4222位所示,包含3个基因:负责MCBs酰胺键合成的基因mcbA、负责MCBs Pictet-Spengler反应的基因mcbB、负责MCBs脱羧的基因mcbC
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)