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1. (WO2014194226) METHODS OF TREATMENT AND COMPOSITIONS WITH XANTHINE OXIDASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/194226 International Application No.: PCT/US2014/040286
Publication Date: 04.12.2014 International Filing Date: 30.05.2014
IPC:
A61K 31/165 (2006.01) ,A61K 31/426 (2006.01) ,A61P 19/06 (2006.01) ,A61K 9/22 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
165
having aromatic rings, e.g. colchicine, atenolol, progabide
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
425
Thiazoles
426
1,3-Thiazoles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19
Drugs for skeletal disorders
06
Antigout agents, e.g. antihyperuricemic or uricosuric agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
22
Sustained or differential release type
Applicants:
TAKEDA PHARMACEUTICALS U.S.A., INC. [US/US]; One Takeda Parkway Deerfield, Illinois 60015, US
TEIJIN PHARMA LIMITED [JP/JP]; 2-1, Kasumigaseki 3-chome Chiyoda-ku, Tokyo 100-0013, JP
Inventors:
GUNAWARDHANA, Lhanoo; US
GUPTE, Vijay; US
NAIK, Himanshu; US
MAYER, Michael; US
KOMATSU, Kanji; JP
Agent:
SHANER, Sandra L.; Cantor Colburn, LLP 20 Church St., 22nd Floor Hartford, Connecticut 06103, US
Priority Data:
61/829,75931.05.2013US
61/839,60926.06.2013US
Title (EN) METHODS OF TREATMENT AND COMPOSITIONS WITH XANTHINE OXIDASE INHIBITORS
(FR) PROCÉDÉS DE TRAITEMENT ET COMPOSITIONS CONTENANT DES INHIBITEURS DE XANTHINE OXYDASE
Abstract:
(EN) Methods and pharmaceutical compositions for reducing number of gout flares experienced by a patient are disclosed. The methods can comprise administering to a patient with hyperuricemia an effective amount of a xanthine oxidase inhibitor in a modified release dosage form once daily or in an immediate release dosage form two or more times daily to prevent at least one gout flare or reduce the number of gout flares experienced by the patient.
(FR) La présente invention concerne des procédés et compositions pharmaceutiques permettant de réduire le nombre d'érythèmes de la goutte chez un patient. Les procédés peuvent inclure l'administration à un patient atteint d'hyperuricémie d'une quantité efficace d'un inhibiteur de xanthine oxydase sous une forme posologique à libération modifiée à raison d'une fois par jour ou sous une forme posologique à libération immédiate à raison de deux fois par jour ou plus pour prévenir au moins un érythème de la goutte ou réduire le nombre d'érythèmes de la goutte chez le patient.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)