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1. (WO2014193969) COMPOUNDS FOR THE TREATMENT OF HYPERTENSION AND HYPERTENSIVE END STAGE RENAL DISEASE

Pub. No.:    WO/2014/193969    International Application No.:    PCT/US2014/039814
Publication Date: Fri Dec 05 00:59:59 CET 2014 International Filing Date: Thu May 29 01:59:59 CEST 2014
IPC: A61K 31/4164
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors: TSIGELNY, Igor, F.
O'CONNOR, Daniel, T.
KOUZNETSOVA, Valentina, L.
BISWAS, Nilima
Title: COMPOUNDS FOR THE TREATMENT OF HYPERTENSION AND HYPERTENSIVE END STAGE RENAL DISEASE
Abstract:
This disclosure relates to compounds and compositions useful for the treatment of hypertension and hypertensive renal disease. Further provided herein is a pharmaceutical composition comprising a compound provided herein, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The compounds provided herein are also useful for treating hypertension or hypertensive end stage renal disease (ESRD) in a patient in need thereof. In some embodiments, the method includes administering to the patient a therapeutically effective amount of a compound provided herein, or a pharmaceutically acceptable salt thereof.