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1. (WO2014193663) 4'-AZIDO, 3'-DEOXY-3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/193663    International Application No.:    PCT/US2014/038288
Publication Date: 04.12.2014 International Filing Date: 15.05.2014
IPC:
A61K 31/7072 (2006.01), A61K 31/7076 (2006.01), C07H 19/04 (2006.01)
Applicants: RIBOSCIENCE LLC [US/US]; 3901 Laguna Avenue Palo Alto, California 94306 (US)
Inventors: SMITH, Mark; (US).
KLUMPP, Klaus G.; (US)
Agent: KISKO, Jennifer L.; Gray Robinson, P.A. P.O. Box 3068 301 E. Pine Street, Suite 1400 Orlando, Florida 32802-3068 (US)
Priority Data:
61/824,034 16.05.2013 US
Title (EN) 4'-AZIDO, 3'-DEOXY-3'-FLUORO SUBSTITUTED NUCLEOSIDE DERIVATIVES
(FR) DÉRIVÉS NUCLÉOSIDIQUES 4'-AZIDO, 3'DÉSOXY-3'-FLUORO SUBSTITUÉS
Abstract: front page image
(EN)The present disclosure relates to 4'-azido, 3'-deoxy-3'-fluoro substituted nucleoside derivatives as inhibitors of HCV replicon RNA replication. Also disclosed are pharmaceutical compositions comprising such compounds and methods of use thereof for the treatment of HCV.
(FR)La présente invention concerne les dérivés nucléosidiques 4'-azido, 3'désoxy-3'-fluoro substitués qui sont utiles en tant qu'inhibiteurs de la réplication d'ARN du réplicon du VHC. L'invention concerne également des compositions pharmaceutiques comprenant de tels composés et des méthodes d'utilisation desdits composés pour le traitement du VHC.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)