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1. (WO2014193468) POLYMER CHELATOR CONJUGATES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/193468 International Application No.: PCT/US2013/067620
Publication Date: 04.12.2014 International Filing Date: 30.10.2013
Chapter 2 Demand Filed: 23.03.2015
IPC:
A61K 31/785 (2006.01) ,A61K 38/17 (2006.01) ,A61P 35/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
74
Synthetic polymeric materials
785
Polymers containing nitrogen
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
04
specific for metastasis
Applicants:
MIMEDX GROUP, INC. [US/US]; 1775 West Oak Commons Court NE Marietta, Georgia 30062-2254, US
Inventors:
KOOB, Thomas J.; US
Agent:
SWISS, Gerald F.; c/o Foley & Lardner LLP 3000 K Street N.W. Suite 600 Washington, District of Columbia 20007-5109, US
Priority Data:
13/903,87828.05.2013US
Title (EN) POLYMER CHELATOR CONJUGATES
(FR) CONJUGUÉS CHÉLATEURS POLYMÈRES
Abstract:
(EN) Provided herein are biocompatible polymer conjugates comprising a biologically compatible polymer covalently bound to a biologically compatible chelator moiety, which in turn are optionally bound, reversibly, to pharmacologically active metal ions. The biologically compatible polymer may comprise of modified biomaterial or tissue grafts composed of at least one membrane, capable of recruiting stem cells in vivo and in vitro. Also described is a novel vacuum drying device and the use thereof.
(FR) L'invention concerne des conjugués polymères biocompatibles comprenant un polymère biologiquement compatible lié par covalence à un groupement chélateur biologiquement compatible, lesquels sont à leur tour éventuellement liés, de manière réversible, à des ions métalliques pharmacologiquement actifs. Le polymère biologiquement compatible peut être constitué d'un biomatériau modifié ou de greffes de tissus composés d'au moins une membrane, susceptible de recruter des cellules souches in vivo et in vitro. L'invention concerne également un dispositif de séchage sous vide d'un nouveau type et son utilisation.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)