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1. (WO2014191940) COPOLYMER AND NANOPARTICLES OBTAINED THEREFROM FOR DRUG DELIVERY
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/191940 International Application No.: PCT/IB2014/061791
Publication Date: 04.12.2014 International Filing Date: 28.05.2014
IPC:
C08G 63/664 (2006.01) ,A61K 9/51 (2006.01) ,A61K 31/765 (2006.01)
Applicants: FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA[IT/IT]; Via Morego, 30 Genova, IT
Inventors: GAGLIARDI, Mariacristina; IT
BIFONE, Angelo; IT
BERTERO, Alice; IT
Agent: CASCIANO, Lidia; Studio Torta S.p.A. Via Viotti, 9 I-10121 Torino, IT
Priority Data:
TO2013A00043128.05.2013IT
Title (EN) COPOLYMER AND NANOPARTICLES OBTAINED THEREFROM FOR DRUG DELIVERY
(FR) COPOLYMÈRE ET NANOPARTICULES OBTENUES À PARTIR DE CELUI-CI ET DESTINÉES À ÊTRE UTILISÉES DANS L'ADMINISTRATION DE MÉDICAMENT
Abstract:
(EN) The present invention concerns a block copolymer composed of two blocks S1 and S2, wherein S1 consists of m(PEG)n, where n is an integer in the range between 4 and 50 and S2 is a random copolymer consisting of the monomer units R1 and R2 where R1 is the monomer unit corresponding to the monomer γ- valerolactone and R2 is the monomer unit corresponding to the monomer selected from the group consisting of ε-caprolactone, δ-valerolactone, β-butyrolactone, ε-caprolactam, δ- valerolactam. A method for the preparation thereof, the use thereof, nanoparticles and a pharmaceutical composition comprising the same is also provided.
(FR) La présente invention concerne un copolymère bloc composé de deux blocs S1 et S2, S1 comprenant m(PEG)n, n étant un nombre entier compris entre 4 et 50, et S2 étant un copolymère aléatoire comprenant les motifs monomères R1 et R2, R1 étant le motif monomère correspondant au monomère γ-valérolactone et R2 étant le motif monomère correspondant au monomère sélectionné dans le groupe comprenant ε-caprolactone, δ-valérolactone, p-butyrolactone, ε-caprolactame, δ- valérolactame. L'invention concerne également un procédé de préparation de ce copolymère, son utilisation, et des nanoparticules et une composition pharmaceutique le comprenant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: Italian (IT)