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1. (WO2014191885) COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS

Pub. No.:    WO/2014/191885    International Application No.:    PCT/IB2014/061687
Publication Date: Fri Dec 05 00:59:59 CET 2014 International Filing Date: Sun May 25 01:59:59 CEST 2014
IPC: A61K 31/185
C07C 57/48
Applicants: CELLIXBIO PRIVATE LIMITED
Inventors: KANDULA, Mahesh
Title: COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS
Abstract:
The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I or formula II, and methods for the treatment of neuromuscular disorders may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of arthritis, congestive heart failure, Parkinson's disease, disuse atrophy, gyrate atrophy, McArdle's disease, Huntington's disease, mitochondrial diseases, muscular dystrophy, neuroprotection and depression.