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1. (WO2014191759) FISH VACCINE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/191759 International Application No.: PCT/GB2014/051655
Publication Date: 04.12.2014 International Filing Date: 30.05.2014
A61K 38/16 (2006.01) ,C07K 14/37 (2006.01) ,C12N 15/62 (2006.01)
Applicants: THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN[GB/GB]; Research & Innovation University Office Kings College Aberdeen Aberdeenshire AB24 3FX, GB
Inventors: WAWRA, Stephan; GB
VAN WEST, Pieter; GB
SECOMBES, Christopher John; GB
Agent: ANDREWS, Robert; Mewburn Ellis LLP City Tower 40 Basinghall Street London, Greater London EC2V 5DE, GB
Priority Data:
(EN) A composition comprising a translocation sequence derived from a fish pathogen and a heterologous payload coupled to the translocation sequence is provided. The composition is able to translocate across the plasma membrane of a eukaryotic cell, for example a fish cell, and thus stimulate an immune response. Accordingly, nucleic acids, vectors, host cells, compositions and vaccines based thereon are also provided.
(FR) Une composition comprenant une séquence de translocation dérivée d'un pathogène de poisson et une charge hétérologue couplée à la séquence de translocation. La composition est capable d'effectuer la translocation à travers la membrane plasmatique d'une cellule eucaryote, par exemple une cellule de poisson, et de de stimuler ainsi une réponse immunitaire. En conséquence, des acides nucléiques, des vecteurs, des cellules hôtes, des compositions et des vaccins à base de ceux-ci sont également divulgués.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)