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1. (WO2014191480) USE OF URINARY HIV NUCLEIC ACIDS TO DIAGNOSE AND MONITOR HIV-ASSOCIATED NEPHROPATHY (HIVAN)
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/191480 International Application No.: PCT/EP2014/061108
Publication Date: 04.12.2014 International Filing Date: 28.05.2014
IPC:
C12Q 1/70 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
70
involving virus or bacteriophage
Applicants: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)[FR/FR]; 101, rue de Tolbiac F-75013 Paris, FR
UNIVERSITÉ PARIS DESCARTES[FR/FR]; 12, rue de l'Ecole de Médecine F-75006 Paris, FR
ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP)[FR/FR]; 3, avenue Victoria F-75004 Paris, FR
Inventors: CANAUD, Guillaume; FR
TERZI, Fabiola; FR
ROUZIOUX, Christine; FR
Agent: HIRSCH, Denise; Inserm Transfert 7 rue Watt F-75013 Paris, FR
Priority Data:
13305697.828.05.2013EP
Title (EN) USE OF URINARY HIV NUCLEIC ACIDS TO DIAGNOSE AND MONITOR HIV-ASSOCIATED NEPHROPATHY (HIVAN)
(FR) UTILISATION DES ACIDES NUCLÉIQUES DU VIH DANS L'URINE POUR DIAGNOSTIQUER ET SURVEILLER UNE NÉPHROPATHIE ASSOCIÉE AU VIH (HIVAN)
Abstract:
(EN) The invention relates to the diagnosis of HIV-associated nephropathy (HIVAN) based on determining the expression level of HIV nucleic acids (HIV RNA and/or DNA) in combination with the renal function of a patient. The invention also relates to a method for distinguishing between HIVAN and non-HIVAN kidney disease in a patient based on the expression level of urinary HIV nucleic acids.
(FR) Cette invention concerne le diagnostic de la néphropathie associée au VIH (HIVAN) basé sur la détermination du niveau d'expression des acides nucléiques du VIH (ARN et/ou ADN du VIH) en association avec la fonction rénale d'un patient. Cette invention concerne également une méthode destinée à distinguer une maladie rénale de type HIVAN et non-HIVAN chez un patient, ladite méthode se basant sur le niveau d'expression des acides nucléiques du VIH dans l'urine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)