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|1. (WO2014191396) TAMPER RESISTANT DOSAGE FORM WITH BIMODAL RELEASE PROFILE|
|Title:||TAMPER RESISTANT DOSAGE FORM WITH BIMODAL RELEASE PROFILE|
The invention relates to a pharmaceutical dosage form comprising: (i) at least one formed segment (S1), which contains a first pharmacologically active ingredient (A1) and provides prolonged release thereof, and (ii) at least one further segment (S2), which contains a second pharmacologically active ingredient (A2) and provides immediate release thereof, wherein the at least one formed segment (S1) exhibits a higher breaking strength than the at least one further segment (S2) and the at least one formed segment (S1) exhibits a breaking strength of more than 500 N.