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1. (WO2014191363) INTERACTIONS OF BETANODAVIRUSES IN INFECTION

Pub. No.:    WO/2014/191363    International Application No.:    PCT/EP2014/060852
Publication Date: Fri Dec 05 00:59:59 CET 2014 International Filing Date: Tue May 27 01:59:59 CEST 2014
IPC: A61K 39/12
Applicants: NOVARTIS TIERGESUNDHEIT AG
UNIVERSITY OF MALAGA
BORREGO, Juan Jose
CARBALLO PEREZ, Carlos
DEL CARMEN ALONSO, Maria
GARCIA-ROSADO, Esther
LOPEZ-JIMENA, Benjamin
RODRIGUEZ, Jose F.
Inventors: BORREGO, Juan Jose
CARBALLO PEREZ, Carlos
DEL CARMEN ALONSO, Maria
GARCIA-ROSADO, Esther
LOPEZ-JIMENA, Benjamin
RODRIGUEZ, Jose F.
Title: INTERACTIONS OF BETANODAVIRUSES IN INFECTION
Abstract:
Disclosed are interactions between different betanodaviruses during infection of cells "in vitro" and in European sea bass. More specifically, fish administered striped jack nervous necrosis viruses (SJNNV), which are then exposed to red-spotted grouper nervous necrosis viruses (RGNNV), have fewer symptoms of disease associated with RGNNV and/or increased survival as compared to fish not administered SJNNV prior to exposure to RGNNV.