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1. (WO2014191356) DIAGNOSIS AND/OR TREATMENT OF DISEASES, WHICH ARE RELATED TO ALLERGIC REACTIONS TO STAPHYLOCOCCUS AUREUS

Pub. No.:    WO/2014/191356    International Application No.:    PCT/EP2014/060841
Publication Date: Fri Dec 05 00:59:59 CET 2014 International Filing Date: Tue May 27 01:59:59 CEST 2014
IPC: G01N 33/569
G01N 33/68
C12Q 1/37
G01N 33/573
Applicants: ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD
Inventors: BRÖKER, Barbara
ENGELMANN, Susanne
HECKER, Michael
STEIL, Leif
VÖLKER, Uwe
BACHERT, Claus
KOLATA, Julia
LINK, Christopher
STENTZEL, Sebastian
Title: DIAGNOSIS AND/OR TREATMENT OF DISEASES, WHICH ARE RELATED TO ALLERGIC REACTIONS TO STAPHYLOCOCCUS AUREUS
Abstract:
The invention suggests methods of diagnosis and therapy of diseases, which are related to allergic reactions to the Staphylococcus aureus and corresponding preparations. For diagnosis an interaction of at least one serine protease like protein of Staphylococcus aureus or a derived protein or peptide with a blood sample or a serum sample or a plasma sample of a patient is analyzed. For the therapeutic aspect at least one serine protease like protein of Staphylococcus aureus or a derived protein or peptide is used as allergen in a systemic immune therapy approach.