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1. (WO2014190356) ANTI-B7-H5 ANTIBODIES AND THEIR USES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/190356    International Application No.:    PCT/US2014/039621
Publication Date: 27.11.2014 International Filing Date: 27.05.2014
Chapter 2 Demand Filed:    05.06.2015    
IPC:
C07K 14/705 (2006.01), C07K 16/28 (2006.01), A61K 39/00 (2006.01)
Applicants: AMPLIMMUNE, INC. [US/US]; 45 W. Watkins Mill Road Gaithersburgh, Maryland 20878 (US).
THE JOHNS HOPKINS UNIVERSITY [US/US]; 3400 N. Charles Street Baltimore, Maryland 21218 (US)
Inventors: CHEN, Lieping; (US).
YAO, Sheng; (US).
LIU, Linda; (US).
LANGERMANN, Solomon; (US)
Agent: PABST, Patrea L.; 1545 Peachtree Street, Suite 320 Atlanta, Georgia 30309 (US)
Priority Data:
61/827,216 24.05.2013 US
Title (EN) ANTI-B7-H5 ANTIBODIES AND THEIR USES
(FR) ANTICORPS ANTI-B7-H5 ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present invention relates to antibodies and their antigen-binding fragments and to other molecules that are capable of immunospecifically binding to the B7-H5 ligand of the B7-H5:CD28H pathway, and to the uses of such molecules in the treatment and diagnosis of autoimmune disease, transplant rejection and other inflammatory diseases.
(FR)La présente invention concerne des anticorps et leurs fragments de liaison à un antigène et d'autres molécules qui sont aptes à se lier de manière immunospécifique au ligand B7-H5 de la voie B7-H5:CD28H, et les utilisations de telles molécules dans le traitement et le diagnostic d'une maladie auto-immune, d'un rejet de greffe et d'autres maladies inflammatoires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)