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1. (WO2014189392) METHODS AND COMPOSITIONS FOR THE DISRUPTION OF BIOFILMS AND TREATMENT OF DISORDERS CHARACTERIZED BY THE PRESENCE OF BIOFILMS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/189392    International Application No.:    PCT/NZ2014/000095
Publication Date: 27.11.2014 International Filing Date: 23.05.2014
Chapter 2 Demand Filed:    12.02.2015    
IPC:
A61K 31/194 (2006.01), A61K 33/02 (2006.01), A61P 11/12 (2006.01), A61P 31/04 (2006.01), A61P 31/00 (2006.01)
Applicants: BREATHE EASY LIMITED [NZ/NZ]; c/o James & Wells Intellectual Property Level 12, KPMG Centre 85 Alexandra Street Hamilton, 3204 (NZ)
Inventors: ELLIOTT, Robert; (NZ)
Agent: CATALYST INTELLECTUAL PROPERTY; Level 5, 111 Customhouse Quay Wellington 6011 (NZ)
Priority Data:
61/826,927 23.05.2013 US
Title (EN) METHODS AND COMPOSITIONS FOR THE DISRUPTION OF BIOFILMS AND TREATMENT OF DISORDERS CHARACTERIZED BY THE PRESENCE OF BIOFILMS
(FR) MÉTHODES ET COMPOSITIONS DESTINÉES À LA RUPTURE DES BIOFILMS ET AU TRAITEMENT DES TROUBLES CARACTÉRISÉS PAR LA PRÉSENCE DE BIOFILMS
Abstract: front page image
(EN)Methods and compositions are provided for the disruption of biofilms and the treatment of disorders characterized by the presence of biofilms and/or abnormally viscous and/or cohesive bodily secretions, such as mucus and sputum. Disorders that can be effectively treated using the disclosed compositions and methods include cystic fibrosis (CF), endocarditis, urinary tract infections, middle-ear infections, chronic sinusitis, gingivitis, periodontal disease, bronchiectasis, chronic obstructive pulmonary disease (COPD), asthma, bronchitis, neonatal meconium aspiration syndrome, smokers' cough, chronic tonsillitis, chronic vaginitis, and fungal or bacterial infections. The compositions, which contain an effective amount of trisodium citrate and ammonium chloride, may be administered alone or in combination with one or more known therapeutic agents.
(FR)La présente invention concerne des méthodes et des compositions destinées à la rupture des biofilms et au traitement des troubles caractérisés par la présence de biofilms et/ou de sécrétions biologiques anormalement visqueuses et/ou cohésives, comme par exemple le mucus et l'expectoration. Les troubles pouvant être efficacement traités en utilisant les compositions et méthodes de la présente invention incluent la fibrose kystique (CF), l'endocardite, les infections des voies urinaires, les infections de l'oreille moyenne, la sinusite chronique, la gingivite, la parodontopathie, la bronchectasie, la bronchopneumopathie chronique obstructive (COPD), l'asthme, la bronchite, le syndrome d'inhalation méconiale néonatal, la toux du fumeur, l'amygdalite chronique, la vaginite chronique, et les infections fongiques ou bactériennes. Les compositions, qui contiennent une quantité efficace de citrate de trisodium et de chlorure d'ammonium, peuvent être administrées seules ou en association avec un ou plusieurs agents thérapeutiques connus.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)