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1. (WO2014189378) BINDING MOLECULES THAT BIND HUMAN COMPLEMENT FACTOR C2 AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/189378    International Application No.:    PCT/NL2014/050327
Publication Date: 27.11.2014 International Filing Date: 22.05.2014
IPC:
C07K 16/18 (2006.01), A61K 39/395 (2006.01)
Applicants: BROTEIO PHARMA B.V. [NL/NL]; Yalelaan 46 NL-3584 CM Utrecht (NL)
Inventors: HACK, Cornelis Erik; (NL).
YILDIZ, Cafer; (NL).
BOON, Louis; (NL).
SIMONS, Petrus Johannes; (NL)
Agent: JANSEN, C.M.; V.O. Carnegieplein 5 2517 KJ Den Haag (NL)
Priority Data:
13168941.6 23.05.2013 EP
Title (EN) BINDING MOLECULES THAT BIND HUMAN COMPLEMENT FACTOR C2 AND USES THEREOF
(FR) MOLÉCULES DE LIAISON QUI SE LIENT AU FACTEUR C2 DU COMPLÉMENT HUMAIN ET UTILISATIONS DE CELUI-CI
Abstract: front page image
(EN)The invention relates to means and methods that relate to binding molecules that bind human complement factor C2. Specific binding molecules are described with specific C2 activity inhibiting properties. Such binding molecules are useful in the treatment of symptoms of various human diseases among which there is inflammatory disease, neuro-inflammatory disease or ischemia-reperfusion (I/R) injury. Disease.
(FR)L'invention concerne des moyens et des procédés relatifs à des molécules de liaison, qui se lient au facteur C2 du complément humain. Les molécules de liaison spécifiques décrites présentent des propriétés spécifiques d'inhibition de l'activité de C2. De telles molécules de liaison sont utiles dans le traitement de symptômes de diverses maladies humaines, y compris une maladie inflammatoire, une maladie neuro-inflammatoire et une lésion ou maladie d'ischémie-reperfusion.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)