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1. (WO2014188440) TETRAHYDRO-2H-PYRANO[3,2-C]ISOCHROMENE-6-ONES AND ANALOGS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/188440    International Application No.:    PCT/IN2013/000679
Publication Date: 27.11.2014 International Filing Date: 01.11.2013
IPC:
C07D 493/04 (2006.01), A61K 31/35 (2006.01), A61P 19/02 (2006.01)
Applicants: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH [IN/IN]; Anusandhan Bhawan Rafi Marg New Delhi 110 001 (IN)
Inventors: JAIN, Shreyans Kumar; (IN).
SIDIQ, Tabasum; (IN).
MEENA, Samdarshi; (IN).
KHAJURIA, Anamika; (IN).
VISHWAKARMA, Ram Asrey; (IN).
BHARATE, Sandip Bibishan; (IN)
Agent: DHAWAN, Ramesh Chander; Lall Lahiri & Salhotra Plot No. B-28, Sector-32, Institutional Area Gurgaon 122001 (IN)
Priority Data:
1565/DEL/2013 24.05.2013 IN
Title (EN) TETRAHYDRO-2H-PYRANO[3,2-C]ISOCHROMENE-6-ONES AND ANALOGS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
(FR) TÉTRAHYDRO-2H-PYRANO[3,2-C]ISOCHROMÈNE-6-ONES ET ANALOGUES POUR LE TRAITEMENT DE TROUBLES INFLAMMATOIRES
Abstract: front page image
(EN)The present invention relates to 2,3,4,4a-tetrahydro-3,4,8,10-tetrahydroxy-2- (hydroxymethyl)-9-methoxypyrano[3,2-c]isochromen-6(10bH)-one analogs of the Formula I, wherein, R, R' and R" are as herein described. In addition, the invention relates to methods of using compounds for treating or preventing various inflammatory disorders such as rheumatoid arthritis, inflammatory bowel disease, psoriasis, asthma and chronic obstructive pulmonary disorder.
(FR)La présente invention concerne des analogues de la 2,3,4,4a-tétrahydro-3,4,8,10-tétrahydroxy-2- (hydroxyméthyl)-9-méthoxypyrano[3,2-c]isochromén-6(10bH)-one de formule I, dans laquelle R, R' et R" sont tels que décrits ici. L'invention concerne en outre des procédés d'utilisation des composés pour traiter ou prévenir une diversité de troubles inflammatoires tels que l'arthrite rhumatoïde, la maladie intestinale inflammatoire, le psoriasis, l'asthme et la bronchopneumopathie obstructive chronique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)