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Machine translation
1. (WO2014188211) HETEROCYCLIC DERIVATES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/188211    International Application No.:    PCT/GB2014/051592
Publication Date: 27.11.2014 International Filing Date: 23.05.2014
Chapter 2 Demand Filed:    18.03.2015    
IPC:
C07D 403/14 (2006.01), C07D 417/14 (2006.01), C07D 471/04 (2006.01), A61K 31/4725 (2006.01), A61P 27/00 (2006.01)
Applicants: KALVISTA PHARMACEUTICALS LIMITED [GB/GB]; Building 227 Tetricus Science Park Porton Down Sailsbury SP4 0JQ (GB)
Inventors: DAVIE, Rebecca Louise; (GB).
EDWARDS, Hannah Joy; (GB).
EVANS, David Michael; (GB).
HODGSON, Simon Teanby; (GB).
MILLER, Iain; (GB).
NOVAK, Andrew Richard; (GB).
SMITH, Alun John; (GB).
STOCKS, Michael John; (GB)
Agent: HALLYBONE, Huw George; Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA (GB)
Priority Data:
61/826,596 23.05.2013 US
61/865,756 14.08.2013 US
Title (EN) HETEROCYCLIC DERIVATES
(FR) DÉRIVÉS HÉTÉROCYCLIQUES
Abstract: front page image
(EN)The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B,W, X, Y and Z are as defined herein.
(FR)La présente invention concerne des composés de formule (I), des compositions comprenant de tels composés; l'utilisation de tels composés en thérapie (par exemple dans le traitement ou la prévention d'une maladie ou d'un état pathologique dans lequel l'activité de la kallikréine plasmatique est impliquée); et des méthodes de traitement de patients par de tels composés; R5, R6, R7, a, B, W, X, Y et Z étant tels que définis dans la description.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)