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1. (WO2014188198) TACROLIMUS AND ANALOGUES THEREOF FOR MEDICAL USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/188198    International Application No.:    PCT/GB2014/051571
Publication Date: 27.11.2014 International Filing Date: 22.05.2014
IPC:
A61K 31/436 (2006.01), A61P 3/04 (2006.01), A61P 3/10 (2006.01), A61P 21/00 (2006.01), A61P 3/00 (2006.01)
Applicants: CHRONOS THERAPEUTICS LIMITED [GB/GB]; c/o Mercer Lewin 41 Cornmarket Street Oxford OX1 3HA (GB)
Inventors: AKOULITCHEV, Alexandre; (GB).
MILWAY, Elizabeth; (GB).
MELLOR, Elizabeth Jane; (GB).
YOUDELL, Michael; (GB)
Agent: AVIDITY IP; Broers Building Hauser Forum 21 J J Thomson Ave Cambridge CB3 0FA (GB)
Priority Data:
1309376.0 24.05.2013 GB
Title (EN) TACROLIMUS AND ANALOGUES THEREOF FOR MEDICAL USE
(FR) TACROLIMUS ET SES ANALOGUES POUR USAGE MÉDICAL
Abstract: front page image
(EN)The present invention relates to a method of treating adverse fat accumulation and related conditions with very low doses of tacrolimus or a close structural analogue thereof. In particular this invention relates to treating adverse fat accumulation and/or sarcopenia and/or metabolic syndrome inpatients by administering tacrolimus in very low dose. Most particularly this invention relates to the use of tacrolimus in treating age related fat accumulation.
(FR)L'invention concerne une méthode pour traiter une accumulation de graisse indésirable et des états associés à de très faibles doses de tacrolimus ou à un analogue structurel proche de celui-ci. L'invention concerne, en particulier le traitement de l'accumulation de graisse indésirable et/ou de la sarcopénie et/ou des malades hospitalisés pour un syndrome métabolique par administration de tacrolimus à très faible dose. L'invention concerne plus particulièrement l'utilisation du tacrolimus pour traiter une accumulation de graisse indésirable liée à l'âge.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)