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Machine translation
1. (WO2014188178) POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/188178    International Application No.:    PCT/GB2014/051547
Publication Date: 27.11.2014 International Filing Date: 21.05.2014
IPC:
C07K 7/62 (2006.01), A61K 38/12 (2006.01)
Applicants: NEW PHARMA LICENCE HOLDINGS LIMITED [MT/MT]; 103 Palazzo Pietro Stiges Strait Street Valletta, VLT 1436 (MT)
Inventors: BROWN, Pamela; (GB).
DAWSON, Michael; (GB).
SIMONOVIC, Mona; (GB).
BOAKES, Steven; (GB).
DUPERCHY, Esther; (GB)
Agent: WILLS, Jonathan; Mewburn Ellis LLP City Tower 40 Basinghall Street London, Greater London EC2V 5DE (GB)
Priority Data:
1309248.1 22.05.2013 GB
1404301.2 11.03.2014 GB
Title (EN) POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS
(FR) DÉRIVÉS POLYMYXINE ET LEUR UTILISATION DANS LE CADRE D'UNE THÉRAPIE COMBINÉE EN ASSOCIATION AVEC D'AUTRES ANTIBIOTIQUES
Abstract: front page image
(EN)Described are compounds of formula (I) for use in combination treatment with a second active agent, such as rifampicin, for example for treatment of a microbial infection. The compound of formula (I) is a polymyxin compound is: where the groups -A-, -R1, -R2, -R3, -R4, -R5, -R6, -R7, -R8, and -X-are described in detail within the description.
(FR)La présente invention concerne des composés de formule (I) destinés à être utilisés dans le cadre d'un traitement combiné avec un second principe actif tel que la rifampicine, pour traiter par exemple une infection microbienne. Le composé de formule (I) est un composé polymyxine dans lequel les groupes -A-, -R1, -R2, -R3, -R4, -R5, -R6, -R7, -R8 et -X- sont tels que décrits en détails dans la description.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)