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1. (WO2014186526) NUCLEIC ACID AMPLIFICATION SIGNAL ACQUISITION AND SIGNAL ANALYSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/186526    International Application No.:    PCT/US2014/038103
Publication Date: 20.11.2014 International Filing Date: 15.05.2014
IPC:
C12Q 1/68 (2006.01)
Applicants: THORNE DIAGNOSTICS, INC. [US/US]; 100 Cummings Center Suite 465E Beverly, MA 01915 (US)
Inventors: BEALS, Thomas, P.; (US)
Agent: POKOTILOW, Steven, B.; Stroock & Stroock & Lavan LLP 180 Maiden Lane New York, NY 10038 (US)
Priority Data:
61/823,564 15.05.2013 US
Title (EN) NUCLEIC ACID AMPLIFICATION SIGNAL ACQUISITION AND SIGNAL ANALYSIS
(FR) ACQUISITION DE SIGNAUX D'AMPLIFICATION D'ACIDES NUCLÉIQUES ET ANALYSE DES SIGNAUX
Abstract: front page image
(EN)Methods and systems are disclosed herein for improvements in real-time data collection and real-time signal analysis for nucleic acid amplification reactions. The present invention provides, in various embodiments, systems and methods for analyzing data obtained from a biochemical amplification reaction. In some embodiments, the amplification reaction is a continuous (i.e., non-cyclic) reaction, from which data (e.g., signal proportional to product accumulation rate) are periodically sampled. In preferred embodiments, the invention uses an amplification reaction for which there exists an explicit mathematical model of the amplification. In alternative embodiments, the invention provides for empirical analysis of amplification reactions for which no explicit rate model exists.
(FR)La présente invention concerne des procédés et des systèmes destinés à améliorer le recueil de données en temps réel et l'analyse de signaux en temps réel dans le domaine des réactions d'amplification d'acides nucléiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)