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1. (WO2014186508) HUMAN EXTENSIVELY SELF-RENEWING ERYTHROBLASTS (ESRE)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/186508    International Application No.:    PCT/US2014/038075
Publication Date: 20.11.2014 International Filing Date: 15.05.2014
IPC:
C12N 5/0789 (2010.01)
Applicants: UNIVERSITY OF ROCHESTER [US/US]; 601 Elmwood Avenue Box Ott Rochester, NY 14642 (US)
Inventors: PALIS, James; (US).
ENGLAND, Samantha; (FR).
KIM, Ah Ram; (US)
Agent: NGUYEN, Quang D.; Riverside Law, LLP 300 Four Falls Corporate Center, Suite 710 300 Conshohocken State Road West Conshohocken, PA 19428 (US)
Priority Data:
61/823,677 15.05.2013 US
Title (EN) HUMAN EXTENSIVELY SELF-RENEWING ERYTHROBLASTS (ESRE)
(FR) ÉRYTHROBLASTES HAUTEMENT AUTO-RENOUVELABLES (ESRE) HUMAINS
Abstract: front page image
(EN)The present invention provides a human cell population that can self-renew extensively and yet retain the capacity to differentiate into red blood cells (RBCs). These cells are referred to as extensively self-renewing erythroblasts (ESREs). The cells of the invention serve among other things as a renewable source of transfusable RBCs.
(FR)La présente invention concerne une population de cellules humaines hautement auto-renouvelables et conservant leur capacité de différentiation dans des globules rouges (RBC). Ces cellules sont appelées érythroblastes hautement auto-renouvelables (ESRE). Les cellules selon l'invention servent, entre autres choses, de source renouvelable de globules rouges destinés à la transfusion.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)