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1. (WO2014185952) METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/185952    International Application No.:    PCT/US2013/066212
Publication Date: 20.11.2014 International Filing Date: 22.10.2013
IPC:
A61K 38/06 (2006.01)
Applicants: STEALTH BIOTHERAPEUTICS CORP [--/MC]; 2nd Floor, Le Prince de Galles 3-5 Avenue des Citronniers MC-98000 Monaco (MC).
HEART INSTITUTE GOOD SAMARITAN HOSPITAL [US/US]; 1225 Wilshire Boulevard Los Angeles, California 90017 (US)
Inventors: WILSON, D. Travis; (US).
KLONER, Robert, A.; (US)
Agent: EWING, James, F.; Foley & Lardner LLP 3000 K Street N.W. Suite 600 Washington, District of Columbia 20007-5106 (US)
Priority Data:
61/823,305 14.05.2013 US
Title (EN) METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING
(FR) MÉTHODES DE PRÉVENTION OU DE TRAITEMENT DU REMODELAGE VENTRICUALIRE GAUCHE
Abstract: front page image
(EN)The disclosure provides methods of preventing, treating, or ameliorating LV remodeling in a mammalian subject. The methods comprise administering to the subject a therapeutic amount of an aromatic-cationic peptide such as D-Arg-2,6-Dmt- Lys-Phe-NH2.
(FR)L'invention concerne des méthodes qui permettent de prévenir, de traiter ou d'atténuer le remodelage ventriculaire gauche chez un sujet mammifère. Ces méthodes consistent à administrer au sujet une dose thérapeutique d'un peptide aromatique-cationique de type D-Arg-2,6-Dmt- Lys-Phe-NH2.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)