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1. (WO2014185908) HYBRIDOMA CLONES, MONOCLONAL ANTIBODIES, AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/185908    International Application No.:    PCT/US2013/041256
Publication Date: 20.11.2014 International Filing Date: 15.05.2013
IPC:
C07K 16/28 (2006.01)
Applicants: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE [US/US]; 445 N. Fifth Street Suite 600 Phoenix, AZ 85004 (US)
Inventors: AZORSA, David; (US)
Agent: FULLER, Rodney, J.; Booth Udall Fuller, PLC 1255 West Rio Salado Parkway Suite 215 Tempe, AZ 85281 (US)
Priority Data:
Title (EN) HYBRIDOMA CLONES, MONOCLONAL ANTIBODIES, AND METHODS OF USE
(FR) CLONES D'HYBRIDOMES, ANTICORPS MONOCLONAUX ET PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)The present invention is directed to a monoclonal antibody that recognizes human CD63 in its native form. The invention is also directed to a hybridoma cell line that produces the monoclonal antibody, and to methods of diagnosing and treating cancer and purifying exosomes using the antibody. The invention is further directed to pharmaceutical compositions comprising an antibody of the invention and a pharmaceutically acceptable carrier.
(FR)La présente invention concerne un anticorps monoclonal qui reconnait CD63 humain dans sa forme native. L'invention concerne également une lignée cellulaire d'hybridomes produisant l'anticorps ainsi que des procédés permettant le diagnostic et le traitement du cancer et la purification d'exosomes à l'aide de l'anticorps.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)