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1. (WO2014185601) PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENOPAUSAL SYMPTOMS CONTAINING FLAVONOID COMPOUND DERIVED FROM TOXICODENDRON VERNICIFLUUM EXTRACT AS ACTIVE INGREDIENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/185601    International Application No.:    PCT/KR2013/009056
Publication Date: 20.11.2014 International Filing Date: 10.10.2013
IPC:
A61K 31/343 (2006.01), A61K 31/353 (2006.01), A61K 36/22 (2006.01), A61P 15/00 (2006.01)
Applicants: LIFETREE BIOTECH. CO. LTD. [KR/KR]; 2F., 43-26, Suin-ro, Gwonseon-gu, Suwon-si, Gyeonggi-do 441-853 (KR)
Inventors: NA, Chun-Soo; (KR).
HONG, Cheol Yi; (KR).
YOON, Sun-Young; (KR).
KIM, Jin-Beom; (KR).
ROH, Hyun-Jung; (KR).
NOH, Hye-Ji; (KR).
UM, Na-Na; (KR).
DONG, Mi-Suk; (KR).
NA, Dae-Seung; (KR)
Agent: CHUNG HYUN PATENT & LAW FIRM; Hanmaum Bldg. 4F., 225, Baumoe-ro Seocho-gu Seoul 137-130 (KR)
Priority Data:
10-2013-0055721 16.05.2013 KR
Title (EN) PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENOPAUSAL SYMPTOMS CONTAINING FLAVONOID COMPOUND DERIVED FROM TOXICODENDRON VERNICIFLUUM EXTRACT AS ACTIVE INGREDIENT
(FR) COMPOSITION PHARMACEUTIQUE POUR LE TRAITEMENT PROPHYLACTIQUE OU THÉRAPEUTIQUE DES SYMPTÔMES DE LA MÉNOPAUSE CONTENANT UN COMPOSÉ FLAVONOÏDE DÉRIVÉ D'UN EXTRAIT DE TOXICODENDRON VERNICIFLUUM AU TITRE DE PRINCIPE ACTIF
(KO) 옻나무 추출물 유래 플라보노이드 화합물을 유효성분으로 하는 갱년기 증후군 예방 및 치료용 약학적 조성물
Abstract: front page image
(EN)The present invention relates to a pharmaceutical composition for preventing or treating menopausal symptoms, the composition containing Toxicodendron vernicifluum extract, or a flavonoid compound derived therefrom or a pharmaceutically acceptable salt thereof, as an active ingredient. The Toxicodendron vernicifluum extract or flavonoid compound derived therefrom of the present invention exhibits activity which is more selective for oestrogen receptor beta (ER-β) than for oestrogen receptor alpha (ER-α) and thus, being a phytoestrogen with fewer side effects, can be used to advantage in preventing and treating menopausal symptoms.
(FR)La présente invention concerne une composition pharmaceutique destinée au traitement prophylactique ou thérapeutique des symptômes de la ménopause, la composition contenant un extrait de Toxicodendron vernicifluum, ou un composé flavonoïde qui en est dérivé ou l'un de ses sels de qualité pharmaceutique, au titre de principe actif. L'extrait de Toxicodendron vernicifluum ou le composé flavonoïde qui en est dérivé selon la présente invention présente une activité qui est plus sélective vis-à-vis du récepteur bêta des œstrogènes (ER-β) que du récepteur alpha des œstrogènes (ER-α) et ainsi, étant un phyto-œstrogène avec moins d'effets secondaires, peut être employé avantageusement dans le traitement prophylactique et thérapeutique des symptômes de ménopause.
(KO)본 발명은 옻나무 추출물, 또는 그 유래 플라보노이드 화합물 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 갱년기 증후군의 예방 및 치료용 약학적 조성물에 관한 것으로, 본 발명의 옻나무 추출물, 또는 그 유래 플라보노이드 화합물은 에스트로겐 수용체 알파(ER-α)보다 에스트로겐 수용체 베타(ER-β)에서 더 선택적인 활성을 나타내기 때문에 부작용이 경감된 식물성 에스트로겐으로서, 갱년기 증후군의 예방 및 치료에 유용하게 이용될 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)