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Machine translation
1. (WO2014184734) MARKERS ASSOCIATED WITH MTOR INHIBITION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/184734    International Application No.:    PCT/IB2014/061396
Publication Date: 20.11.2014 International Filing Date: 13.05.2014
IPC:
C12Q 1/68 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel (CH).
CHEN, David [US/US]; (US) (US only).
TARAN, Tetiana [UA/US]; (US) (US only).
ROBINSON, Douglas Michael [US/US]; (US) (US only)
Inventors: CHEN, David; (US).
TARAN, Tetiana; (US).
ROBINSON, Douglas Michael; (US)
Agent: GRUBER, Markus; Novartis Pharma AG Postfach CH-4002 Basel (CH)
Priority Data:
61/823,160 14.05.2013 US
61/830,300 03.06.2013 US
61/881,604 24.09.2013 US
Title (EN) MARKERS ASSOCIATED WITH MTOR INHIBITION
(FR) MARQUEURS ASSOCIÉS À L'INHIBITION DE MTOR
Abstract: front page image
(EN)The present invention relates to methods for predicting sensitivity of a cancer patient for treatment with an mTOR inhibitor wherein minimal genetic alterations in the PI3K pathway and FGFR pathways and CCND1 are indicative of a higher benefit from mTOR therapy.
(FR)La présente invention concerne des procédés permettant de prédire la sensibilité d'un patient cancéreux à un traitement par inhibiteur de mTOR, des altérations génétiques minimales dans la voie PI3K et les voies FGFR et CCND1 indiquant un bénéfice supérieur du traitement par mTOR.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)