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1. (WO2014184631) USE OF A THIAZOLO PYRIMIDINONE FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/184631    International Application No.:    PCT/IB2014/000707
Publication Date: 20.11.2014 International Filing Date: 12.05.2014
IPC:
A61K 31/519 (2006.01), A61P 1/00 (2006.01)
Applicants: TORRENT PHARMACEUTICALS LIMITED [IN/IN]; Torrent House Off Ashram Road, Gujarat 380009 Ahmedabad (IN)
Inventors: DUTT, Chaitanya; (IN).
CHAUTHAIWALE, Vijay; (IN).
GUPTA, Ram; (IN).
ZAMBAD, Shitalkumar; (IN).
DESHPANDE, Shailesh; (IN).
KOTECHA, Jignesh; (IN).
GUPTA, Ramesh; (IN).
SRIVASTAVA, Sanjay; (IN).
CHHIPA, Laxmikant; (IN).
ABRAHAM, Jaya; (IN)
Agent: ARVIND, Chitra; Rajeshwari & Associates Amsoft Business Centre, Unitech Trade Center Sector-43 Gurgaon 122002 Haryana (IN)
Priority Data:
1718/MUM/2013 14.05.2013 IN
2309/MUM/2013 09.07.2013 IN
Title (EN) USE OF A THIAZOLO PYRIMIDINONE FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
(FR) COMPOSITION PHARMACEUTIQUE FAIBLEMENT DOSÉE
Abstract: front page image
(EN)Present invention relates to a low dose pharmaceutical composition, preferably oral composition comprising therapeutically effective amount of [(2-hydroxy-4-oxo-6,7,8,9- tetrahydro-4H,5H-10-thia-1,4a-diaza-benzo[a]azulene-3-carbonyl)-amino]-acetic acid (compound A) in the range of 2.5 mg to 60 mg. Present invention also relates to a method of treating inflammatory bowel disease in a mammal by administrating said low dose pharmaceutical composition. Further, present invention relates to a use of the compound A for the preparation of low dose pharmaceutical composition for the treatment of inflammatory bowel disease in a mammal.
(FR)La présente invention concerne une composition pharmaceutique faiblement dosée, de préférence une composition à administrer par voie orale comprenant une quantité thérapeutiquement efficace d'acide [(2-hydroxy-4-oxo-6,7,8,9- tétrahydro-4H,5H-10-thia-1,4a-diaza-benzo[a]azulène-3-carbonyl)-amino]-acétique (composé A) dans la plage allant de 2,5 mg à 60 mg. La présente invention concerne également un procédé de traitement d'une affection abdominale inflammatoire chez un mammifère par administration de ladite composition pharmaceutique faiblement dosée. En outre, la présente invention concerne une utilisation du composé A pour la préparation d'une composition pharmaceutique faiblement dosée pour le traitement d'une affection abdominale inflammatoire chez un mammifère.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)