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Pub. No.:    WO/2014/184545    International Application No.:    PCT/GB2014/051469
Publication Date: 20.11.2014 International Filing Date: 14.05.2014
C07K 16/00 (2006.01), C07K 16/10 (2006.01)
Applicants: ISIS INNOVATION LIMITED [GB/GB]; Ewert House Ewert Place, Summertown Oxford Oxfordshire OX2 7SG (GB)
Inventors: SCANLAN, Christopher, Neil; .
CRISPIN, Matthew, David, Max; (GB).
YU, Xiaojie; (CA)
Agent: WEBBER, Philip, Michael; Dehns St Bride's House 10 Salisbury Square London Greater London EC4Y 8JD (GB)
Priority Data:
1308658.2 14.05.2013 GB
Abstract: front page image
(EN)The present invention relates to polypeptides, proteins and antibodies comprising a FcγRIIB-binding domain. The invention further relates to methods of suppressing immune cell activation or immuno-suppression, and particularly to methods of treating inflammatory and autoimmune disorders using such polypeptides, proteins and antibodies.
(FR)L'invention concerne des polypeptides, de protéines et des anticorps comprenant un domaine de liaison à FcγRIIB. L'invention concerne également des méthodes de suppression de l'activation de cellules immunitaires ou d'immuno-suppression, et en particulier des méthodes de traitement des troubles inflammatoires et auto-immuns au moyen de ces polypeptides, protéines et anticorps.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)