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1. (WO2014184365) SULPHAMOYLTHIOPHENAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/184365    International Application No.:    PCT/EP2014/060132
Publication Date: 20.11.2014 International Filing Date: 16.05.2014
IPC:
C07D 333/34 (2006.01), C07D 409/12 (2006.01)
Applicants: JANSSEN SCIENCES IRELAND UC [IE/IE]; Eastgate Village Eastgate Little Island Co Cork (IE)
Inventors: VANDYCK, Koen; (BE).
HACHÉ, Geerwin Yvonne Paul; (BE).
LAST, Stefaan Julien; (BE).
VERSCHUEREN, Wim Gaston; (BE).
RABOISSON, Pierre Jean-Marie Bernard; (BE)
Agent: VAN WANROOIJ, Eva; Turnhoutseweg 30 B-2340 Beerse (BE)
Priority Data:
13168295.7 17.05.2013 EP
13185227.9 19.09.2013 EP
14157917.7 05.03.2014 EP
Title (EN) SULPHAMOYLTHIOPHENAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
(FR) DÉRIVÉS DE SULPHAMOYLTHIOPHÉNAMIDES ET LEUR UTILISATION EN TANT QUE MÉDICAMENTS POUR LE TRAITEMENT DE L'HÉPATITE B
Abstract: front page image
(EN)Inhibitors of HBV replication of formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X and R1 to R8 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
(FR)L'invention concerne des inhibiteurs de la réplication du VHB de formule (I), y compris des formes stéréochimiquement isomères, et des sels, hydrates et solvates de ceux-ci; X et R1 à R8 ayant la signification donnée dans le descriptif. La présente invention concerne également des procédés de préparation desdits composés, des compositions pharmaceutiques les contenant et leur utilisation, seuls ou en combinaison avec d'autres inhibiteurs du VHB, pour le traitement du VHB.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)