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1. (WO2014184350) SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/184350    International Application No.:    PCT/EP2014/060102
Publication Date: 20.11.2014 International Filing Date: 16.05.2014
IPC:
C07D 207/40 (2006.01), A61K 31/401 (2006.01), A61P 31/00 (2006.01)
Applicants: JANSSEN SCIENCES IRELAND UC [IE/IE]; Eastgate Village Eastgate Little Island Co Cork (IE)
Inventors: VANDYCK, Koen; (BE).
HACHÉ, Geerwin, Yvonne, Paul; (BE).
LAST, Stefaan, Julien; (BE).
MC GOWAN, David, Craig; (BE).
ROMBOUTS, Geert; (BE).
VERSCHUEREN, Wim, Gaston; (BE).
RABOISSON, Pierre, Jean-Marie, Bernard; (BE)
Agent: VAN WANROOIJ, Eva; Turnhoutseweg 30 B-2340 Beerse (BE)
Priority Data:
13168291.6 17.05.2013 EP
13175181.0 04.07.2013 EP
13182281.9 29.08.2013 EP
13191209.9 31.10.2013 EP
13198160.7 18.12.2013 EP
14157900.3 05.03.2014 EP
Title (EN) SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
(FR) DÉRIVÉS DE SULFAMOYLPYRROLAMIDES ET LEUR UTILISATION EN TANT QUE MÉDICAMENTS POUR LE TRAITEMENT DE L'HÉPATITE B
Abstract: front page image
(EN)Inhibitors of HBV replication of Formula (ID) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X, Ra to Rd and R4 to R6 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
(FR)L'invention concerne des inhibiteurs de la réplication du VHB de formule (ID), y compris des formes stéréochimiquement isomères, et des sels, hydrates et solvates de ceux-ci, formule dans laquelle X, Ra à Rd et R4 à R6 sont tels que définis dans la description. La présente invention concerne également des procédés de préparation desdits composés, des compositions pharmaceutiques les contenant et leur utilisation, seuls ou en association avec d'autres inhibiteurs du VHB, pour le traitement du VHB.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)