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1. (WO2014184248) TRPA1 ANTAGONIST COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/184248    International Application No.:    PCT/EP2014/059853
Publication Date: 20.11.2014 International Filing Date: 14.05.2014
IPC:
C07C 275/18 (2006.01), C07D 217/06 (2006.01), C07D 401/04 (2006.01), C07D 403/04 (2006.01), C07D 413/04 (2006.01), C07D 417/04 (2006.01), C07D 211/34 (2006.01), C07D 295/16 (2006.01)
Applicants: ACTURUM LIFE SCIENCE AB [SE/SE]; c/o PEAB Fastighetsutveckling Sverige AB P.O. Box 808 S-169 28 Solna (SE)
Inventors: SVENSSON, Mats A; (US).
WEIGELT, Dirk; (SE)
Agent: NEELISSEN-SUBNEL, Marianne; Swea IP Law AB Box 44 151 21 Södertälje (SE)
Priority Data:
61/823,706 15.05.2013 US
Title (EN) TRPA1 ANTAGONIST COMPOUNDS
(FR) COMPOSÉS ANTAGONISTES DE TRPA1
Abstract: front page image
(EN)Compounds of Formula (I), pharmaceutically acceptable salts thereof, diastereomers, enantiomers, or mixtures thereof: wherein R1, R2, R3, X, Yn and A are as defined in the specification, as well as pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
(FR)L'invention porte sur des composés de la formule (I), des sels pharmaceutiquement acceptables de ces derniers, des diastéréomères, des énantiomères, ou des mélanges de ces derniers : où R1, R2, R3, X, Yn et A sont tels que définis dans la description, ainsi que sur des compositions pharmaceutiques renfermant lesdits composés. Les composés selon l'invention sont utiles pour la thérapie, en particulier pour la gestion de la douleur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)