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1. (WO2014183850) ARYLQUINAZOLINES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/183850    International Application No.:    PCT/EP2014/001236
Publication Date: 20.11.2014 International Filing Date: 08.05.2014
IPC:
C07D 405/14 (2006.01), C07D 401/10 (2006.01), C07D 403/10 (2006.01), C07D 405/04 (2006.01), C07D 417/10 (2006.01), C07D 417/14 (2006.01), C07D 471/04 (2006.01), C07D 487/04 (2006.01), C07D 491/048 (2006.01), C07D 495/04 (2006.01), C07D 498/08 (2006.01), C07D 513/04 (2006.01), A61K 31/506 (2006.01), A61K 31/519 (2006.01), A61P 35/00 (2006.01)
Applicants: MERCK PATENT GMBH [DE/DE]; Frankfurter Strasse 250 64293 Darmstadt (DE)
Inventors: FUCHSS, Thomas; (DE).
EMDE, Ulrich; (DE).
BUCHSTALLER, Hans-Peter; (DE).
MEDERSKI, Werner; (DE)
Priority Data:
10 2013 008 118.1 11.05.2013 DE
Title (DE) ARYLCHINAZOLINE
(EN) ARYLQUINAZOLINES
(FR) ARYLCHINAZOLINE
Abstract: front page image
(DE)Die Erfindung betrifft neuartige Verbindungen der Formel (I), die zur Hemmung von Serin- Threonin-Proteinkinasen sowie zur Sensibilisierung von Krebszellen gegenüber Antikrebsmitteln und/oder ionisierender Strahlung verwendet werden können.
(EN)The invention relates to novel compounds of formula (I) that can be used to inhibit serine/threonine protein kinases and to sensitize cancer cells with respect to anti-cancer agents and/or ionizing radiation.
(FR)L'invention concerne de nouveaux composés de formule (I) qui peuvent être utilisés pour l'inhibition des protéines sérine-thréonine kinases et pour la sensibilisation de cellules cancéreuses contre des agents anticancéreux et/ou un rayonnement ionisant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)