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1. (WO2014183017) IMPROVED DELIVERY OF RNA INTERFERING AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/183017    International Application No.:    PCT/US2014/037470
Publication Date: 13.11.2014 International Filing Date: 09.05.2014
IPC:
A61K 31/7052 (2006.01)
Applicants: KIPPERMAN, Richard, M. as Chapter 7 Bankruptcy Trustee for TRAVERSA THERAPEUTICS, INC. [US/US]; (US)
Inventors: WARD, Gary, H.; (US).
BRADSHAW, Curt, W.; (US)
Agent: TAHMASSEBI, Sam, K.; (US)
Priority Data:
61/821,649 09.05.2013 US
Title (EN) IMPROVED DELIVERY OF RNA INTERFERING AGENTS
(FR) ADMINISTRATION AMÉLIORÉE D'AGENTS D'INTERFÉRENCE D'ARN
Abstract: front page image
(EN)Provided are compositions for the delivery of biomolecules, such as nucleic acids into target cells, and methods of making and using same. The compositions comprise nucleic acid delivery complexes that include a nucleic acid, such as an RNA interfering agent, an RNA neutralization domain, a double stranded RNA binding domain, and a protein transduction domain.
(FR)L'invention concerne des compositions pour l'administration de biomolécule, telles que des acides nucléiques dans des cellules cibles, et leurs procédés de fabrication et d'utilisation. Les compositions comprennent des complexes d'administration d'acide nucléique qui comprennent un acide nucléique, tel qu'un agent d'interférence d'ARN, un domaine de neutralisation d'ARN, un domaine de liaison d'ARN à double brin et un domaine de transduction de protéine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)