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1. (WO2014181886) HYBRID GEL CONTAINING PARTICULATE DECELLULARIZED TISSUE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/181886    International Application No.:    PCT/JP2014/062544
Publication Date: 13.11.2014 International Filing Date: 02.05.2014
IPC:
A61L 27/00 (2006.01), A61K 9/06 (2006.01), A61K 35/12 (2006.01), A61K 35/28 (2006.01), A61K 35/30 (2006.01), A61K 35/34 (2006.01), A61K 35/407 (2006.01), A61K 35/42 (2006.01), A61K 38/43 (2006.01), A61K 38/48 (2006.01), A61P 9/10 (2006.01)
Applicants: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE [JP/JP]; 1-6-1 Okubo, Kita-ku, Kumamoto-shi, Kumamoto 8608568 (JP).
NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY [JP/JP]; 1-5-45, Yushima, Bunkyo-ku, Tokyo 1138510 (JP).
SAPPORO MEDICAL UNIVERSITY [JP/JP]; 291-85, Minami 1-jo Nishi 17-chome, Chuo-ku, Sapporo-shi, Hokkaido 0608556 (JP).
ADEKA CORPORATION [JP/JP]; 2-35, Higashiogu 7-chome, Arakawa-ku, Tokyo 1168554 (JP)
Inventors: MATSUDA, Junichi; (JP).
MIYABASHIRA, Sumika; (JP).
HARANO, Satomi; (JP).
KISHIDA, Akio; (JP).
KIMURA, Tsuyoshi; (JP).
NEGISHI, Jun; (JP).
HIGAMI, Tetsuya; (JP).
FUNAMOTO, Seiichi; (JP).
HIWATARI, Ken-ichiro; (JP).
TASAKI, Akiko; (JP)
Agent: SAMEJIMA, Mutsumi; AOYAMA & PARTNERS, Umeda Hankyu Bldg. Office Tower, 8-1, Kakuda-cho, Kita-ku, Osaka-shi, Osaka 5300017 (JP)
Priority Data:
2013-097399 07.05.2013 JP
Title (EN) HYBRID GEL CONTAINING PARTICULATE DECELLULARIZED TISSUE
(FR) GEL HYBRIDE CONTENANT UN TISSU DÉCELLULARISÉ PARTICULAIRE
(JA) 粒子状脱細胞化組織を含むハイブリッドゲル
Abstract: front page image
(EN)Provided are: a hybrid gel that contains a particulate decellularized tissue (a product prepared by grinding a decellularized biological tissue that is obtained by decellularizing a biological tissue derived from an animal), fibrinogen and thrombin; a cell culture base material containing the hybrid gel; a method for preparing the hybrid gel; and a kit containing a particulate decellularized tissue and an adhesive for biological tissues. The hybrid gel according to the present invention has an effect of promoting the differentiation and function acquisition of stem cells and therapeutic effects on various diseases.
(FR)La présente invention concerne un gel hybride qui contient un tissu décellularisé particulaire (un produit préparé par broyage d'un tissu biologique décellularisé qui est obtenu par décellularisation d'un tissu biologique dérivé d'un animal), du fibrinogène et de la thrombine ; un matériau de base pour culture cellulaire ; et un kit comprenant un tissu décellularisé particulaire et un adhésif pour tissus biologiques. Le gel hybride selon la présente invention a un effet de promotion de la différenciation et de l'acquisition de fonctions des cellules souches et des effets thérapeutiques sur différentes maladies.
(JA)粒子状脱細胞化組織(動物由来の生体組織を脱細胞化処理して得られた脱細胞化生体組織が粉砕したもの)、フィブリノゲン、及びトロンビンを含むハイブリッドゲル、当該ハイブリッドゲルを含む細胞培養基材、当該ハイブリッドゲルの作製方法、及び粒子状脱細胞化組織及び生体組織接着剤を含むキットを提供する。本発明のハイブリッドゲルは、幹細胞の分化や機能獲得を促進する効果、各種疾患に対する治療効果を有する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)