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1. (WO2014180562) NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/180562    International Application No.:    PCT/EP2014/001202
Publication Date: 13.11.2014 International Filing Date: 06.05.2014
IPC:
C07D 333/36 (2006.01), A61K 31/381 (2006.01), C07D 409/12 (2006.01), C07D 409/14 (2006.01), C07D 413/12 (2006.01), C07D 417/12 (2006.01), A61P 43/00 (2006.01)
Applicants: GALAPAGOS NV [BE/BE]; Generaal de Wittelaan L11/A3 B-2800 Mechelen (BE)
Inventors: VAN DER PLAS, Steven; (BE).
MAMMOLITI, Oscar; (BE).
MENET, Christel; (BE).
TRICARICO, Giovanni; (BE).
DE BLIECK, Ann; (BE).
JOANESSE, Caroline; (BE).
DE MUNCK, Tom; (BE).
KELGTERMANS, Hans; (BE)
Agent: GALAPAGOS NV; Generaal de Wittelaan L11 A3 B-2800 Mechelen (BE)
Priority Data:
13081377 07.05.2013 GB
2523 09.08.2013 BS
13179320 10.10.2013 GB
Title (EN) NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS
(FR) NOUVEAUX COMPOSÉS ET LEURS COMPOSITIONS PHARMACEUTIQUES POUR LE TRAITEMENT DE LA MUCOVISCIDOSE
Abstract: front page image
(EN)The present invention discloses compounds according to Formula (I), wherein R1, R2, R3, L, and the subscript m are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions, and methods of treatment using the same, for the treatment of cystic fibrosis by administering a compound of the invention.
(FR)La présente invention concerne des composés répondant à la formule (I), où R1, R2, R3, L et l'indice m sont tels que définis dans la description. La présente invention concerne des composés et leur utilisation dans le traitement de la mucoviscidose, leurs procédés de production, des compositions pharmaceutiques et des méthodes de traitement les utilisant, pour le traitement de la mucoviscidose par l'administration d'un composé de l'invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)