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1. (WO2014178931) SOBETIROME IN THE TREATMENT OF MYELINATION DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/178931    International Application No.:    PCT/US2014/014943
Publication Date: 06.11.2014 International Filing Date: 05.02.2014
IPC:
A61K 38/24 (2006.01), A61P 25/00 (2006.01), A61P 25/28 (2006.01), C07C 59/48 (2006.01)
Applicants: SCANLAN, Thomas, S. [US/US]; (US) (US only).
HARTLEY, Meredith [US/US]; (US) (US only).
PLACZEK, Andrew [US/US]; (US) (US only).
RIGHI, Marco [IT/IT]; (IT) (US only).
BOURDETTE, Dennis [US/US]; (US) (US only).
MARRACCI, Gail [US/US]; (US) (US only).
CHAUDHARY, Priya [US/US]; (US) (US only).
OREGON HEALTH & SCIENCE UNIVERSITY [US/US]; 0690 SW Bancroft Street, Mail Code L106TT Portland, OR 97239 (US) (For All Designated States Except US).
THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS [US/US]; Office of General Counsel- PSG IV (024) 810 Vermont Avenue N.W. Washington, DC 20420 (US) (For All Designated States Except US)
Inventors: SCANLAN, Thomas, S.; (US).
HARTLEY, Meredith; (US).
PLACZEK, Andrew; (US).
RIGHI, Marco; (IT).
BOURDETTE, Dennis; (US).
MARRACCI, Gail; (US).
CHAUDHARY, Priya; (US)
Agent: CONNOLLY, Jodi, L.; Klarquist Sparkman, LLP One World Trade Center, Suite 1600 121 SW Salmon Street Portland, OR 97204 (US)
Priority Data:
61/819,467 03.05.2013 US
PCT/US2013/0053640 05.08.2013 US
Title (EN) SOBETIROME IN THE TREATMENT OF MYELINATION DISEASES
(FR) UTILISATION DE SOBÉTIROME DANS LE TRAITEMENT DE MALADIES OU DE PATHOLOGIES ASSOCIÉES À LA MYÉLINISATION
Abstract: front page image
(EN)Methods of treating a subject having or at risk of developing a neurodegenerative disease or condition associated with demyelination, insufficient myelination, or underdevelopment of myelin sheath are described. The methods include administration of a therapeutically effective amount of sobetirome, or a pharmaceutically acceptable salt thereof.
(FR)L'invention concerne des méthodes de traitement d'un sujet ayant ou présentant un risque de développer une maladie neurodégénérative ou un état associé à une démyélinisation, à une myélinisation insuffisante ou à un sous-développement de la gaine de myéline. Les méthodes comprennent l'administration d'une quantité thérapeutiquement efficace de sobétirome, ou d'un sel de qualité pharmaceutique de sobétirome.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)