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1. (WO2014178552) ENDOCARDIUM-DERIVED ADULT STEM CELLS AND METHOD FOR PRODUCING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/178552    International Application No.:    PCT/KR2014/003313
Publication Date: 06.11.2014 International Filing Date: 16.04.2014
IPC:
C12N 5/074 (2010.01), C12N 5/02 (2006.01), A61K 35/12 (2006.01)
Applicants: SEOUL NATIONAL UNIVERSITY HOSPITAL [KR/KR]; 101, Daehak-ro, Jongno-gu, Seoul 110-744 (KR)
Inventors: KIM, Hyo-Soo; (KR).
YANG, Han-Mo; (KR).
KIM, Ju-Young; (KR).
CHO, Hyun-Jai; (KR)
Agent: LEE, Myoung-Jin; MJ International Patent Law Firm 6th floor, 28, Yeongdong-daero 85-gil Gangnam-gu Seoul 135-846 (KR)
Priority Data:
10-2013-0048486 30.04.2013 KR
Title (EN) ENDOCARDIUM-DERIVED ADULT STEM CELLS AND METHOD FOR PRODUCING SAME
(FR) CELLULES SOUCHES ADULTES DÉRIVÉES DE L'ENDOCARDE ET LEUR PROCÉDÉ DE PRODUCTION
(KO) 심장내막 유래의 성체줄기세포 및 이의 제조방법
Abstract: front page image
(EN)The present invention relates to endocardium-derived adult stem cells obtained by culturing peripheral blood mononuclear cells (PBMCs) separated from peripheral blood, and a cell therapeutic agent for treating cardiovascular diseases containing the same as an active ingredient. The adult stem cells, according to the present invention, have an origin that is the endocardium and strong blood vessel formation, and is thus remarkably useful for treating cardiovascular diseases such as ischemia, myocardial infarction, and the like.
(FR)La présente invention concerne des cellules souches adultes dérivées de l'endocarde obtenues par culture de cellules mononuclées de sang périphérique (PBMC) séparées du sang périphérique, et un agent thérapeutique cellulaire pour le traitement des maladies cardiovasculaires les contenant comme ingrédient actif. Les cellules souches adultes, selon la présente invention, ont une origine au niveau de la formation de l'endocarde et de vaisseaux sanguins solides, et sont ainsi remarquablement utiles pour le traitement des maladies cardiovasculaires telles que l'ischémie, l'infarctus du myocarde, et similaires.
(KO)본 발명은, 말초혈액에서 분리된 말초혈액단핵세포(PBMC)를 배양함으로써 수득되는 심장내막 유래의 성체줄기세포, 및 이를 유효성분으로 함유하는 혈관질환 치료용 세포치료제에 관한 것이다. 본 발명에 따른 성체줄기세포는 그 기원이 심장의 내막이고 강한 혈관형성능을 갖기 때문에 허혈이나 심근경색 등의 심혈관계질환의 치료에 크게 유용하다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)