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1. (WO2014178152) LOCALLY ADMINISTERED LIPOSOME AND APPLICATION THEREFOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/178152    International Application No.:    PCT/JP2013/080367
Publication Date: 06.11.2014 International Filing Date: 01.11.2013
IPC:
A61K 9/127 (2006.01), A61K 31/519 (2006.01), A61K 31/7088 (2006.01), A61K 31/713 (2006.01), A61K 45/00 (2006.01), A61K 47/18 (2006.01), A61K 47/24 (2006.01), A61K 47/48 (2006.01), A61K 48/00 (2006.01), A61P 35/00 (2006.01), A61P 43/00 (2006.01), C12N 15/09 (2006.01), C12N 15/113 (2010.01)
Applicants: DELTA-FLY PHARMA, INC. [JP/JP]; 37-2, Nishikino, Miyajima,Kawauchi-cho, Tokushima-shi, Tokushima 7710116 (JP)
Inventors: ISHIDA, Tatsuhiro; (JP)
Agent: HIRAKI, Yusuke; Atago Green Hills MORI Tower 32F, 5-1, Atago 2-chome, Minato-ku, Tokyo 1056232 (JP)
Priority Data:
2013-095950 30.04.2013 JP
Title (EN) LOCALLY ADMINISTERED LIPOSOME AND APPLICATION THEREFOR
(FR) LIPOSOME ADMINISTRÉ LOCALEMENT ET APPLICATION ASSOCIÉE
(JA) 局所投与用リポソームおよびその用途
Abstract: front page image
(EN) The purpose of the present invention is to provide a novel delivery means capable of efficiently delivering an active ingredient to target cells. A locally administered liposome unmodified by PEG and devoid of cholesterol, the liposome being composed of dioleoyl phosphatidyl ethanolamine (DOPE), phosphatidylcholine, and a cationic lipid.
(FR) Le but de la présente invention est de fournir un nouveau moyen de libération capable de libérer de façon efficace un ingrédient actif dans des cellules cibles. L'invention porte également sur un liposome administré localement non modifié par PEG et dépourvu de cholestérol, le liposome étant composé de dioléoyl phosphatidyl éthanolamine (DOPE), de phosphatidylcholine, et d'un lipide cationique.
(JA) 本発明は、標的とする細胞に活性成分を効率的に送達することが可能な新たな送達手段を提供するこ とを目的とする。 ジオレイルホスファチジルエタノールアミン(DOPE)、ホスファチジルコリン及びカチオン性脂質からなり、PEGで修飾されておらず、かつコレステロールを含まない、局所投与用リポソーム。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)