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Machine translation
1. (WO2014178001) "INHIBITORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE, COMPOSITIONS, PRODUCTS AND USES THEREOF"
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/178001    International Application No.:    PCT/IB2014/061080
Publication Date: 06.11.2014 International Filing Date: 29.04.2014
IPC:
C07D 401/04 (2006.01), A61K 31/4439 (2006.01), A61K 31/4406 (2006.01), A61K 31/4427 (2006.01), A61P 29/00 (2006.01), A61P 17/00 (2006.01), A61P 35/00 (2006.01), A61P 3/10 (2006.01)
Applicants: UNIVERSITÀ DEGLI STUDI DEL PIEMONTE ORIENTALE "AMEDEO AVOGADRO" [IT/IT]; Via Duomo, 6 I-13100 Vercelli (IT)
Inventors: GENAZZANI, Armando A.; (IT).
TRON, Gian Cesare; (IT).
GALLI, Ubaldina; (IT).
TRAVELLI, Cristina; (IT).
CUZZOCREA, Salvatore; (IT).
GROSA, Giorgio; (IT).
SORBA, Giovanni; (IT).
CANONICO, Pier Luigi; (IT)
Agent: FREYRIA FAVA, Cristina; c/o Buzzi, Notaro & Antonielli d'Oulx S.r.l. Via Maria Vittoria, 18 I-10123 Torino (IT)
Priority Data:
TO2013A000356 03.05.2013 IT
Title (EN) "INHIBITORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE, COMPOSITIONS, PRODUCTS AND USES THEREOF"
(FR) "INHIBITEURS DE NICOTINAMIDE PHOSPHORIBOSYLTRANSFÉRASE, COMPOSITIONS, PRODUITS ET LEURS UTILISATIONS"
Abstract: front page image
(EN)Compounds of formula (I): able to inhibit nicotinamide phosphoribosyltransferase. The disclosure also relates to the use of compounds of formula (I) for treatment of pathological conditions in which NAMPT inhibition might be beneficial, such as acute and chronic inflammation, cancer and metabolic disorders.
(FR)Composés de formule (I) capables d'inhiber la nicotinamide phosphoribosyltransférase. Cette invention concerne également l'utilisation des composés de formule (I) pour traiter les états pathologiques où l'inhibition de la NAMPT pourrait s'avérer bénéfique, tels que l'inflammation aiguë et chronique, le cancer et les troubles métaboliques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)