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1. (WO2014177629) A MULTIPART FLUID SYSTEM AND A SYSTEM FOR REGIONAL CITRATE ANTICOAGULATION WITH A PHOSPHATE COMPRISING ANTICOAGULATION FLUID
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/177629    International Application No.:    PCT/EP2014/058852
Publication Date: 06.11.2014 International Filing Date: 30.04.2014
IPC:
A61K 9/08 (2006.01), A61K 31/194 (2006.01), A61K 31/7004 (2006.01), A61K 33/10 (2006.01), A61K 33/14 (2006.01), A61K 33/42 (2006.01), A61P 7/08 (2006.01), A61M 1/34 (2006.01)
Applicants: GAMBRO LUNDIA AB [SE/SE]; P.O. Box 10101 S-220 10 Lund (SE)
Inventors: ÅHL, Petra; (SE).
GODALY, Gabriela; (SE).
NILSSON, Anders; (SE).
STERNBY, Jan; (SE).
WIESLANDER, Anders; (SE)
Agent: JÖNSSON, Anneli; P.O. Box 10101 S-220 10 Lund (SE)
Priority Data:
1350533-4 30.04.2013 SE
Title (EN) A MULTIPART FLUID SYSTEM AND A SYSTEM FOR REGIONAL CITRATE ANTICOAGULATION WITH A PHOSPHATE COMPRISING ANTICOAGULATION FLUID
(FR) SYSTÈME DE FLUIDE MULTICOMPOSANT ET SYSTÈME ANTICOAGULANT RÉGIONAL À BASE DE CITRATE AVEC UN FLUIDE ANTICOAGULANT COMPRENANT DU PHOSPHATE
Abstract: front page image
(EN)The present invention concerns a multipart fluid system for dialysis therapy, wherein the multipart fluid system comprises an anticoagulation fluid and at least one treatment fluid from the group consisting of dialysis fluid and infusion fluids. According to the invention the anticoagulation fluid comprises 10-40 mM citrate, and 0.1-2.0 mM phosphate; and the at least one treatment fluid comprises 0-5 mM total calcium, 0-8 mM citrate, and 0.1-2.0 mM phosphate; with provisos that the at least one treatment fluid comprises citrate when total calcium concentration is 0 mM; and the at least one treatment fluid comprises calcium when the citrate concentration is 0 mM. The present invention further concerns a system for regional citrate anticoagulation in an extracorporeal blood circuit.
(FR)La présente invention concerne un circuit de fluide multicomposant pour thérapie de dialyse, le système de fluide multicomposant comprenant un fluide anticoagulant et au moins un fluide de traitement dans le groupe constitué de fluide de dialyse et de fluides de perfusion. Selon l’invention, le fluide anticoagulant comprend de 10 à 40 mM de citrate, et de 0,1 à 2,0 mM de phosphate ; et l’au moins un fluide de traitement comprend de 0 à 5 mM de calcium total, de 0 à 8 mM de citrate, et de 0,1 à 2,0 mM de phosphate ; à condition que l’au moins un fluide de traitement comprenne du citrate lorsque la concentration de calcium total est de 0 mM ; et l’au moins un fluide de traitement comprend du calcium lorsque la concentration de citrate est de 0 mM. La présente invention concerne en outre un système pour anticoagulant régional à base de citrate dans un circuit sanguin extracorporel.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)