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Machine translation
1. (WO2014177492) BIOCATALYTIC PROCESS FOR THE PRODUCTION OF (R)-3-QUINUCLIDINOL
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/177492    International Application No.:    PCT/EP2014/058547
Publication Date: 06.11.2014 International Filing Date: 28.04.2014
IPC:
C12P 17/12 (2006.01)
Applicants: CAMBREX IEP GMBH [DE/DE]; Rheingaustrasse 190 - 196 65203 Wiesbaden (DE)
Inventors: TSCHENTSCHER, Anke; (DE).
DUPONT, Maria; (DE).
GUPTA, Antje; (DE)
Agent: PLATE SCHWEITZER ZOUNEK PAE; Rheingaustrasse 196 65203 Wiesbaden (DE)
Priority Data:
10 2013 104 418.2 30.04.2013 DE
Title (EN) BIOCATALYTIC PROCESS FOR THE PRODUCTION OF (R)-3-QUINUCLIDINOL
(FR) PROCÉDÉ BIOCATALYTIQUE DE PRODUCTION DE (R)-3-QUINUCLIDINOL
Abstract: front page image
(EN)Process for production of (R)-3-Quinuclidinol by reduction of Quinuclidin-3-one with cofactor and oxidoreductase, characterized in that, the oxidoreductase comprises an amino acid sequence motif MQX1REX2X3WEA, wherein each of X1, X2, X3 are any of amino acid residues A (Ala), R (Arg), N (Asn), D (Asp), C (Cys), Q (Gln), E (Glu), G (Gly), H (His), I (Ile), L (Leu), K (Lys), M (Met), F (Phe), P (Pro), S (Ser), T (Thr), W (Trp), Y (Tyr) or V (Val).
(FR)L'invention concerne un procédé de production de (R)-3-quinuclidinol par réduction de quinuclidin-3-one avec un cofacteur et une oxydoréductase, caractérisé en ce que l'oxydoréductase comprend un motif de séquence d'acides aminés MQX1REX2X3WEA, chacun des X1, X2, X3 étant l'un quelconque des résidus d'acide aminé A (Ala), R (Arg), N (Asn), D (Asp), C (Cys), Q (Gln), E (Glu), G (Gly), H (His), I (Ile), L (Leu), K (Lys), M (Met), F (Phe), P (Pro), S (Ser), T (Thr), W (Trp), Y (Tyr) ou V (Val).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)