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1. (WO2014177479) PRODRUGS OF NAPROXEN AND DICLOFENAC
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/177479    International Application No.:    PCT/EP2014/058530
Publication Date: 06.11.2014 International Filing Date: 28.04.2014
Chapter 2 Demand Filed:    26.09.2014    
IPC:
A61K 47/48 (2006.01), A61P 29/00 (2006.01)
Applicants: LARSEN, Claus Selch [DK/DK]; (DK)
Inventors: LARSEN, Claus Selch; (DK).
LARSEN, Susan Weng; (DK).
THING, Mette Agergaard; (DK).
KRISTENSEN, Jesper Langgaard; (DK).
JENSEN, Henrik; (DK).
ØSTERGAARD, Jesper; (DK)
Agent: CHAS. HUDE A/S; H.C. Andersens Boulevard 33 DK-1780 København V (DK)
Priority Data:
PA 2013 70236 30.04.2013 DK
PA 2013 70289 28.05.2013 DK
Title (EN) PRODRUGS OF NAPROXEN AND DICLOFENAC
(FR) PROMÉDICAMENTS DE NAPROXÈNE ET DE DICLOFÉNAC
Abstract: front page image
(EN)The present invention relates to a compound of formula (I): wherein R1 is R3 -IPU and R2 is the acyloxy residue of diclofenac or naproxen, and specified by the following structures (A) wherein OH-R3 -IPU is selected from (B) and R4 and R5 may be the same or different selected from (C) and salts, solvates and hydrates thereof.
(FR)La présente invention concerne un composé de formule (I) : où R1 est R3 -IPU et R2 est le résidu acyloxy du diclofénac ou du naproxène et spécifié par les structures suivantes où OH-R3 -IPU est sélectionné à partir de et R4 et R5 peuvent être identiques ou différents et sélectionnés à partir de et leurs sels, solvates et hydrates.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)