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1. (WO2014177469) DIAMINOPYRAZINE COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/177469    International Application No.:    PCT/EP2014/058462
Publication Date: 06.11.2014 International Filing Date: 25.04.2014
IPC:
C07D 409/14 (2006.01), C07D 471/04 (2006.01), C07D 401/14 (2006.01), A61P 11/00 (2006.01), A61K 31/497 (2006.01), A61K 31/517 (2006.01)
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE/DE]; Binger Str. 173 55216 Ingelheim Am Rhein (DE)
Inventors: HECKEL, Armin; (DE).
KLEY, Joerg; (DE)
Agent: SIMON ET AL, Elke; Boehringer Ingelheim GmbH Corporate Patents Binger Str. 173 55216 Ingelheim Am Rhein (DE)
Priority Data:
13165963.3 30.04.2013 EP
Title (EN) DIAMINOPYRAZINE COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF
(FR) COMPOSÉS DE DIAMINOPYRAZINE, MÉDICAMENTS CONTENANT LESDITS COMPOSÉS, LEUR UTILISATION ET LEURS PROCÉDÉS DE PRÉPARATION
Abstract: front page image
(EN)The present invention relates to compounds of general formula (I) and the tautomers and the salts thereof, particularly the pharmaceutically acceptable salts thereof with inorganic or organic acids and bases, which have valuable pharmacological properties, particularly an inhibitory effect on epithelial sodium channels and the use thereof for the treatment of diseases, particularly diseases of the lungs and airways.
(FR)La présente invention concerne des composés de formule générale (I) et leurs tautomères et sels, en particulier leurs sels pharmaceutiquement acceptables avec des acides et bases inorganiques ou organiques, qui possèdent également des propriétés pharmacologiques intéressantes, en particulier un effet inhibiteur sur les canaux sodiques épithéliaux, et leur utilisation pour le traitement de maladies, notamment de maladies des poumons et des voies respiratoires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)